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Bilateral basal ganglial necrosis after allogeneic bone marrow transplantation in a child with Kostmann syndrome

Abstract

A 6-year-old girl underwent allogeneic BMT from a matched sibling donor for the treatment of Kostmann syndrome. She suddenly became drowsy on day 30 after BMT, and lost consciousness 2 days later. Cranial CT scan showed symmetrical lesions suggesting bilateral necrosis in the basal ganglia. Clinical and laboratory investigations failed to reveal any evidence of neuro- metabolic disease.

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Suga, N., Nagatoshi, Y., Gondou, K. et al. Bilateral basal ganglial necrosis after allogeneic bone marrow transplantation in a child with Kostmann syndrome. Bone Marrow Transplant 23, 515–517 (1999). https://doi.org/10.1038/sj.bmt.1701595

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  • DOI: https://doi.org/10.1038/sj.bmt.1701595

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