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Bone marrow transplantation from a cadaveric donor

Bone Marrow Transplantation volume 21, pages 857–858 (1998)Cite this article

Abstract

A 2.5-year-old girl with neurogenic Gaucher’s disease was transplanted with donor bone marrow from her HLA-compatible 12-year-old brother whose marrow was harvested 30 min post-mortem, after he suffered a severe head and neck injury. The marrow was stored in liquid nitrogen for 30 days prior to infusion. The post-transplantation period was uneventful with good engraftment and no signs of graft-versus-host disease. Currently, 6 months post-allogeneic bone marrow transplantation (alloBMT), analysis of both bone marrow and blood samples by PCR documented only cells of donor origin. This case demonstrates the feasibility of cadaveric marrow as a source of donor cells. To our knowledge, this patient is the only survivor of alloBMT from a cadaveric donor.

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Authors and Affiliations

  1. Department of Bone Marrow Transplantation, Hadassah University Hospital, Jerusalem, Israel

    J Kapelushnik, T Pugatsch, S Samuel & S Slavin

  2. Department of Pediatrics, Hadassah University Hospital, Jerusalem, Israel

    M Aker

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  1. J Kapelushnik
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  2. M Aker
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  3. T Pugatsch
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  4. S Samuel
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  5. S Slavin
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Kapelushnik, J., Aker, M., Pugatsch, T. et al. Bone marrow transplantation from a cadaveric donor. Bone Marrow Transplant 21, 857–858 (1998). https://doi.org/10.1038/sj.bmt.1701165

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  • DOI: https://doi.org/10.1038/sj.bmt.1701165

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