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Complete heart block in association with graft-versus-host disease

Bone Marrow Transplantation volume 21, pages 85–88 (1998)Cite this article

Abstract

An infant who received haploidentical BM for severe combined immunodeficiency (SCID) developed acute, reversible complete heart block in association with an exacerbation of GVHD. Respiratory distress and myocardial dysfunction were also seen with this and previous GVHD exacerbations. The patient had not received chemotherapy or radiation prior to BMT. The complete heart block resolved after 1 week of intensive immunosuppression. The association of complete heart block with GVHD is important because the heart block is potentially reversible with prompt, aggressive control of the GVHD.

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Authors and Affiliations

  1. Divisions of Hematology/Oncology, University of Iowa College of Medicine, Iowa City, IA, USA

    AL Gilman, S Rumelhart, M Holida, N Lee & F Goldman

  2. Divisions of Intensive Care, University of Iowa College of Medicine, Iowa City, IA, USA

    NW Kooy

  3. Divisions of Cardiology, Department of Pediatrics, University of Iowa College of Medicine, Iowa City, IA, USA

    DL Atkins

  4. Divisions of Department of Medicine, University of Iowa College of Medicine, Iowa City, IA, USA

    Z Ballas

Authors
  1. AL Gilman
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  2. NW Kooy
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  3. DL Atkins
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  4. Z Ballas
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  5. S Rumelhart
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  6. M Holida
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  7. N Lee
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  8. F Goldman
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Gilman, A., Kooy, N., Atkins, D. et al. Complete heart block in association with graft-versus-host disease. Bone Marrow Transplant 21, 85–88 (1998). https://doi.org/10.1038/sj.bmt.1701038

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  • DOI: https://doi.org/10.1038/sj.bmt.1701038

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