Abstract
A PAPER by Zajicek and Datta1 describing the presence of a high concentration of acetylcholine esterase or ‘true’ cholinesterase in the thrombocytes of rat blood recently came to my attention. I have known for some time that considerable ‘true’ cholinesterase is to be found in the white layer of centrifuged rat blood, and while I was working at the Medical Research Laboratories of the Defence Research Board, Ottawa, Canada, I showed by substrate and inhibitor studies that this is a typical ‘true’ cholinesterase. It was my opinion at that time that the enzyme was in the leucocytes rather than in the platelets; but in all other respects my work with rat blood confirmed the findings of the above authors.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Zajicek, I., and Datta, N., Acta Haematologica, 7, 39 (1952).
McCance, R. A., Hutchinson, A. O., Dean, R. F. A., and Jones, P. E. H., Biochem. J., 45, 493 (1949).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
HINES, B. Acetylcholine Esterase of the White Components of Blood. Nature 170, 78–79 (1952). https://doi.org/10.1038/170078b0
Issue Date:
DOI: https://doi.org/10.1038/170078b0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.