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Treatment of relapsed non-Hodgkin’s lymphoma after BEAM chemotherapy and autologous transplantation by BU/CY chemotherapy and salvage transplantation

Bone Marrow Transplantation volume 19, pages 527–528 (1997)Cite this article

Abstract

We report a patient with centroblastic non-Hodgkin’s MALT lymphoma of the stomach treated initially with surgery and post-operative chemotherapy and radiotherapy. First relapse was treated with high-dose BEAM chemotherapy and autologous peripheral blood stem cell transplantation (PBSCT). Second, systemic relapse was treated with high-dose BU/CY and second PBSCT. Today, the patient is in complete remission at 27+ months. The case indicates a curative potential for high-dose BU/CY chemotherapy as salvage therapy for relapsed high-grade lymphoma after BEAM and autologous PBSCT. This may have implications for the prevention as well as for the management of lymphoma relapse after high-dose chemotherapy (HDC) and autologous PBSCT.

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Authors and Affiliations

  1. Division of Hematology and Oncology, Department of Internal Medicine, University of Freiburg Medical Center, Freiburg im Breisgau, Germany

    S Fetscher, M Lübbert, D Behringer, J Finke, R Mertelsmann & W Lange

  2. University of Tübingen Medical Center, Tübingen am Neckar, Germany

    L Kanz

Authors
  1. S Fetscher
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  2. M Lübbert
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  3. L Kanz
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  4. D Behringer
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  5. J Finke
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  6. R Mertelsmann
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  7. W Lange
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Fetscher, S., Lübbert, M., Kanz, L. et al. Treatment of relapsed non-Hodgkin’s lymphoma after BEAM chemotherapy and autologous transplantation by BU/CY chemotherapy and salvage transplantation. Bone Marrow Transplant 19, 527–528 (1997). https://doi.org/10.1038/sj.bmt.1700690

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  • DOI: https://doi.org/10.1038/sj.bmt.1700690

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