Low Toxicity of the Diphtherial Culture Filtrate and its Relation to the Absence of Tyrosine in the Medium

Abstract

I HAVE already shown1 that the diphtherial culture filtrate harvested from the chemically defined media (A.M.C. and A.M.T. medium) containing two (asparagine, DL-methionine) or three amino-acids (asparagine, DL-methionine and L-cystin) as a nitrogen source had a very low toxicity for guinea pigs, while it showed a high degree of flocculation units.

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References

  1. 1

    Yoneda, M., Nagoya J. Med. Sci., 14, No. 2 (in the press, 1951).

  2. 2

    Yoneda, M., Jap. J. Bact., 15, 401 (1950); and in the press; Nature, [167, 860 (1951) ].

  3. 3

    Mueller, J. H., and Miller, P. A., J. Immunol., 40, 21 (1940).

  4. 4

    Seki, T., Ōsaka Igakkai Z., 42, 1397 (1943) (in Japanese).

  5. 5

    Linggood and Woiwod, Nature, 163, 4163 (1949).

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YONEDA, M. Low Toxicity of the Diphtherial Culture Filtrate and its Relation to the Absence of Tyrosine in the Medium. Nature 168, 879–880 (1951). https://doi.org/10.1038/168879a0

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