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Hormonal Control of Liver Catalase

Abstract

Recent investigations of the depressing action of tumours on liver catalase have suggested that this was due to the release by tumours into the circulation of some toxic material1,2. Working with mice, a sex difference in normal liver catalase-level (male > female) as well as a larger percentage depression in males 48 hr. after the injection of tumour material have been observed2. These results indicated some degree of hormonal control of liver catalase-level, and the suggestion was made that the effect of castration and adrenalectomy might be worth investigating.

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References

  1. Nakahara, W., and Fukuoka, F., Gann., 40, 45 (1949).

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  2. Adams, D. H., Brit. J. Cancer, 4, 183 (1950).

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  3. Begg, R. W., and Reynolds, E. F., Science, 111, 721 (1950).

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Adams, D. Hormonal Control of Liver Catalase. Nature 166, 952–953 (1950). https://doi.org/10.1038/166952b0

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