Letter | Published:

A Simple Gasometric Method for the Analysis of the Fermentation-inhibiting properties of Antimicrobic Agents

Naturevolume 166page188 (1950) | Download Citation



RECENTLY, Heim and Poe in the United States introduced a very convenient method for evaluating antimicrobial properties of organic compounds1. They used, for example, Aerobacter aerogenes and Saccharomyces cerevisiœ as test strains, and based the estimation on the volume of gas found on incubation in lactose and glucose broth respectively for 72 hr. or less at 37° C. We have applied the same principle as a convenient method for estimating fermentation-inhibiting properties.

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  1. 1

    Heim, H. C., and Poe, C. F., Food Tech., 2, 23 (1948).

  2. 2

    Nederlandse Warenwet, Jam- Limonadebesluit, Staatsblad 1937, nr. 854; nadere wijziging dd 13 Augustus 1948, Staatsblad I, 369, Methoden van Onderzoek, Art. 20.

  3. 3

    Challinor, S. W., Kieser, M. E., and Pollard, A., Nature, 161, 1023 (1948).

  4. 4

    Wolff, L. K., and Julius, H. W., Annal. Inst. Pasteur, 62, 616 (1939).

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  1. Central Institute for Nutrition Research T.N.O., 61 Catharijnesingel, Utrecht

    • D. A. A. MOSSEL


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