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Identity of a Muscle-inhibiting Flavone in Lucerne

Abstract

IT was suggested in an earlier note1 that the flavone isolated from lucerne which, like most flavones, inhibits smooth-muscle movements, was 3′,4′,5-trihydroxy-7-methoxyflavone. Further work on larger quantities of the flavone purified by high-vacuum sublimation has now shown it to be tricin, 5,7,4′-trihydroxy-3′,5′-dimethoxyflavone, a flavone found in Triticum dicoccum2.

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References

  1. Ferguson, W. S., Ashworth, de B., and Terry, R. A., Nature, 163, 606 (1949).

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  2. Anderson, J. A., Can. J. Res., 9, 80 (1933).

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FERGUSON, W., ASHWORTH, D. & TERRY, R. Identity of a Muscle-inhibiting Flavone in Lucerne. Nature 166, 116–117 (1950). https://doi.org/10.1038/166116a0

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