Abstract
ERGOTHIONEINE has been isolated from ergot1 and from mammalian blood2,3. Barger and Ewins4 and Akabori5 showed that the structure of ergothioneine (I) is β-2-thiolglyoxaline-4(5)-propiobetaine. This structure has now been confirmed by synthesis according to the following scheme.
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HEATH, H., LAWSON, A. & RIMINGTON, C. Synthesis of Ergothioneine. Nature 166, 106 (1950). https://doi.org/10.1038/166106a0
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DOI: https://doi.org/10.1038/166106a0
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