Letter | Published:

Separation of Carboxylate Ions on the Paper Chromatogram

Naturevolume 166pages6667 (1950) | Download Citation



THE work of Martin and Synge1 on the separation of amino-acids by partition chromatography on silica gel has led to the application of this method to the separation of other groups of structurally similar compounds. Lester Smith2 and Ramsey and Patterson3,4 have separated by this means the straight-chain fatty acids containing one to ten carbon atoms, and Elsden5 has put the procedure on a quantitative basis in the case of acetic, propionic and n-butyric acids.

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  1. 1

    Martin, A. J. P., and Synge, R. L. M., Biochem. J., 35, 1358 (1941).

  2. 2

    Lester Smith, E., Biochem. J., 36, Proc. xxii (1942).

  3. 3

    Ramsey, L. L., and Patterson, W. I., J. Assoc. Official Agric. Chem., 28, 644 (1945).

  4. 4

    Ramsey, L. L., and Patterson, W. I., J. Assoc. Official Agric. Chem., 31, 139 (1948).

  5. 5

    Elsden, S. R., Biochem. J., 40, 252 (1946).

  6. 6

    Lugg, J. W. H., and Overell, B. T., Nature, 160, 87 (1947).

  7. 7

    Fink, K., and Fink, R. M., Proc. Soc. Exp. Biol. Med., 70, 654 (1949).

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  1. Bristol University Fruit and Vegetable Preservation Research Station, Campden, Glos

    • F. BROWN
    •  & L. P. HALL


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