Letter | Published:

Occurrences in Normal Human Sera of ‘Incomplete’ Forms of ‘Cold’ Auto–Antibodies

Nature volume 166, page 36 (01 July 1950) | Download Citation

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Abstract

THE existence of ‘incomplete’ forms of antibodies active against human erythrocytes and detectable by means of the Coombs test1 is now widely recognized. Rh antibodies are commonly present in this form, and so are some at least of the recently recognized rarer immune antibodies2, such as anti-Kell and anti-S. The fact that the iso-antibodies anti-A and anti-B may similarly exist in incomplete forms is also being increasingly realized3.

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References

  1. 1.

    , , and , Brit. J. Exp. Path., 26, 255 (1945).

  2. 2.

    Leading article, Lancet, July 16, 1949.

  3. 3.

    , Blood, special issue No. 2, 66 (1948).

  4. 4.

    , and , first meeting of the International Society of Hematology, Buffalo (1948).

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Affiliations

  1. Department of Pathology, Postgraduate Medical School of London, London, W.12. March 2.

    • J. V. DACIE

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DOI

https://doi.org/10.1038/166036a0

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