Letter | Published:

Occurrences in Normal Human Sera of ‘Incomplete’ Forms of ‘Cold’ Auto–Antibodies

Naturevolume 166page36 (1950) | Download Citation



THE existence of ‘incomplete’ forms of antibodies active against human erythrocytes and detectable by means of the Coombs test1 is now widely recognized. Rh antibodies are commonly present in this form, and so are some at least of the recently recognized rarer immune antibodies2, such as anti-Kell and anti-S. The fact that the iso-antibodies anti-A and anti-B may similarly exist in incomplete forms is also being increasingly realized3.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Coombs, R. R. A., Mourant, A. E., and Race, R. R., Brit. J. Exp. Path., 26, 255 (1945).

  2. 2

    Leading article, Lancet, July 16, 1949.

  3. 3

    Witebsky, E., Blood, special issue No. 2, 66 (1948).

  4. 4

    Levine, P., and Wigod, M., first meeting of the International Society of Hematology, Buffalo (1948).

Download references

Author information


  1. Department of Pathology, Postgraduate Medical School of London, London, W.12

    • J. V. DACIE


  1. Search for J. V. DACIE in:

About this article

Publication history

Issue Date



Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.