Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Biological Assay of Small Quantities of Desoxycorticosterone Acetate

Nature volume 166, pages 32–33 (1950)Cite this article

Abstract

ALTHOUGH early studies on the adrenalectomized dog1 have led to means of assay for desoxycorticosterone acetate and for extracts of the adrenal cortex in quantity2–4, no satisfactory micro-assay has hitherto been described.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Loeb, R. F., Atchley, D. W., Benedict, E. M., and Leland, J., J. Exp. Med., 57, 775 (1933).

    Article  CAS  Google Scholar 

  2. Hartman, F. A., and Spoor, H. J., Endocrin., 26, 871 (1940).

    Article  CAS  Google Scholar 

  3. Harrop, G. A., and Thorn, G. W., J. Exp. Med., 65, 757 (1937)

    Article  CAS  Google Scholar 

  4. Hartman, F. A., Lewis, L. A., and Thatcher, J., Proc. Soc. Exp. Biol. Med., 48, 60 (1941).

    Article  CAS  Google Scholar 

  5. Spencer, A. G. (in the press).

  6. Berry, J. W., Chappell, D. G., and Barnes, R. B., Indust. and Eng. Chem. (Anal. Edit.), 18, 19 (1946).

    Article  CAS  Google Scholar 

  7. Bliss, C. I., Indust. Eng. Chem., 12, 84 (1941).

    Google Scholar 

  8. Fisher, R. A., “Statistical Methods for Research Workers” (Oliver and Boyd, Edinburgh).

Download references

Author information

Authors and Affiliations

  1. Departments of Medicine of the College of Physicians and Surgeons, New York

    A. G. SPENCER

  2. University College Hospital Medical School, London, W.C.1

    A. G. SPENCER

Authors
  1. A. G. SPENCER
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

SPENCER, A. Biological Assay of Small Quantities of Desoxycorticosterone Acetate. Nature 166, 32–33 (1950). https://doi.org/10.1038/166032a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/166032a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing