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Fluoroacetate and the Tricarboxylic Acid Cycle in Nematode Parasites

Abstract

CONCEPTIONS of the mode of action of fluoroacetate are varied and conflicting, according to the biological material studied1–5. Another reaction of fluoroacetate, in nematode parasites, in which it appears to inhibit oxidation within the Krebs tricarboxylic acid cycle, is reported here.

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References

  1. Bartlett, G. R., and Barron, E. S. G., J. Biol. Chem., 170, 67 (1947).

    CAS  Google Scholar 

  2. Kalnitsky, G., and Barron, E. S. G., J. Biol. Chem., 170, 83 (1947).

    CAS  Google Scholar 

  3. Kalnitsky, G., and Barron, E. S. G., Archiv. Biochem., 19, 75 (1948).

    CAS  Google Scholar 

  4. Bueding, E., J. Exp. Med., 89, 107 (1949).

    Article  CAS  Google Scholar 

  5. Black, S., and Hutchens, J. C., Archiv. Biochem., 17, 211 (1948).

    CAS  Google Scholar 

  6. Pucher, G. W., Sherman, C. C., and Vickery, H. B., J. Biol. Chem., 113, 235 (1936).

    CAS  Google Scholar 

  7. Krebs, H. A., and Eggleston, F., Biochem. J., 38, 426 (1944).

    Article  CAS  Google Scholar 

  8. Seevers, M. H., and Shideman, F. E., Science, 94, 351 (1941).

    Article  ADS  CAS  Google Scholar 

  9. Massey, V., and Rogers, W. P., Aust. J. Sci. Res., B (in the press).

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MASSEY, V., ROGERS, W. Fluoroacetate and the Tricarboxylic Acid Cycle in Nematode Parasites. Nature 165, 681–682 (1950). https://doi.org/10.1038/165681b0

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