A Reaction between a Deaminase and Heart Actin, and Inhibition of the Effect with Cardiac Glycoside

Abstract

IN a previous paper1, we have shown that when preparing heart actin a contamination followed the actin. This contamination, which apparently is a deaminase, acted on the adenosine triphosphate in the actin and thus prevented the polymerization of the actin to a very great extent. A little adenosine triphosphate added to the solution from outside strongly catalysed the effect of the deaminase.

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References

  1. 1

    Snellman, O., and Gelotte, B., Exp. Cell Res. (in the press).

  2. 2

    Horváth, L., Király, C., and Szerb, J., Nature, 184, 792 (1949).

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SNELLMAN, O., GELOTTE, B. A Reaction between a Deaminase and Heart Actin, and Inhibition of the Effect with Cardiac Glycoside. Nature 165, 604 (1950). https://doi.org/10.1038/165604a0

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