VIRIDIN, an antibiotic produced by a pigment-forming strain of the common soil fungus Trichoderma viride, was first described by Brian and McGowan1, and Brian, Curtis, Hemming and McGowan2. Viridin is not anti-bacterial but is highly antifungal. Its activity against certain fungi is remarkably high. Germination of the spores of, for example, Botrytis allii is prevented by a concentration of 0.019 p.p.m. of α-viridin or 0.156 p.p.m. of β-viridin. Among synthetic fungicides, only the organo-mercurials are of the same order of activity.

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  1. 1

    Brian, P. W., and McGowan, J. C., Nature, 156, 144 (1945).

  2. 2

    Brian, P. W., Curtis, P. J., Hemming, H. G., and McGowan, J. C., Ann. App. Biol., 33, 190 (1946).

  3. 3

    Girard, A., and Sandulesco, G., Helv. Chem. Acta, 19, 1905 (1936).

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VISCHER, E., HOWLAND, S. & RAUDNITZ, H. Viridin. Nature 165, 528 (1950).

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