Abstract
THE attempts by various workers to find a satisfactory substitute for bovine albumin as a suspension medium in the (antigen + univalent antibody) reacting system have been reviewed by Mourant1. The polydispersoid polysaccharides known as dextrans2 possess certain properties which we considered might enable them to replace bovine albumin in such a system. This supposition has been well substantiated in respect of the use of the substance as a diluent for univalent anti-D in routine grouping procedures.
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References
Mourant, A. E., “The Rh Blood Groups and their Clinical Effects”(H.M. Stationery Office, 1948).
Bull, J. P., Ricketts, C., Squire, J. R., Maycock, W. d'A., Spooner, S. J. L., Mollison, P. L., and Patterson, J. C. S., Lancet, i, 134 (1949).
Grubb, R., J. Clin. Path., 2, 223 (1949).
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JONES, A. Dextran as a Diluent for Univalent Antibodies. Nature 165, 118–119 (1950). https://doi.org/10.1038/165118a0
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DOI: https://doi.org/10.1038/165118a0
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