Amino-acid Composition of Bence–Jones Protein


OUR knowledge of the amino-acid composition of Bence–Jones protein is still incomplete. Recently, Dent1 has analysed a specimen of Bence–Jones protein, using paper partition chromatography, with regard to its amino-acid composition. He found that the specimen contained all the common amino-acids except methionine and hydroxyproline. Dent's findings were at variance with those of Devine2, who found methionine present in amount 0.58 per cent.


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PAPASTAMATIS, S., KENCH, J. & WILKINSON, J. Amino-acid Composition of Bence–Jones Protein. Nature 164, 961 (1949).

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