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Difference between Morphine and Synthetic Analgesics in their Actions on Ganglionic Transmission

Abstract

THE analgesic actions of certain new synthetic compounds, including pethidine and amidone, have been extensively compared with that of morphine1. It is assumed that this analgesic action is mainly due to a central effect, although the possible local anæsthetic properties of these compounds have not been investigated.

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References

  1. Schaumann, O., Arch. exp. Path. Pharm., 196, 109 (1940). Thorp, R. H., Walton, E., and Ofner, P., Nature, 160, 605 (1947).

    Article  CAS  Google Scholar 

  2. Brindley, C. O., Fed. Proc., 3, 5 (1944). Greig, M. E., and Howell, R. S., Proc. Soc. Exp. Biol. Med., 68, 352 (1948)

    Google Scholar 

  3. Kibjakow, A. W., PflĂ¼gers Arch., 232, 432 (1933).

    Article  Google Scholar 

  4. Gruber, Ch. M., Hart E., Ross, and Gruber, Ch. M., J. Pharmacol., 73 319 (1941).

    CAS  Google Scholar 

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HEBB, C., KONZETT, H. Difference between Morphine and Synthetic Analgesics in their Actions on Ganglionic Transmission. Nature 163, 720–721 (1949). https://doi.org/10.1038/163720a0

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