PRESENT knowledge of chromosome structure is based chiefly on observations made on fixed preparations of large mitotic chromosomes or of the so-called giant chromosomes in the salivary gland of certain diptera with microscopes utilizing visible or ultra-violet light1. A preliminary account has recently been published of electron microscope studies on large plant chromosomes2. Little or nothing is known concerning the structure of chromosomes in resting cells beyond the fact that they are present in the form of exceedingly slender threads (chromonemata) or of the so-called chromatin network3.
This is a preview of subscription content, access via your institution
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Get just this article for as long as you need it
Prices may be subject to local taxes which are calculated during checkout
Cf. Caspersson, T., Skand. Arch. Physiol., 73, Suppl. 8 (1936).
Buchholz, J. T., Science, 105, 607 (1947).
Cf. Serra, J. A., Portug. Acta Biol., 2, 25 (1947).
Schryver, J., M.S. thesis, Polytechnic Inst., Brooklyn (1948).
Hillier, J., and Ramberg, E. G., J. App. Phys., 18, 48 (1947).
Williams, R. C., and Wyckoff, R. W. G., J. App. Phys., 15, 712 (1944).
Mirsky, A. E., and Ris, H., J. Gen. Physiol., 31, 1 (1947).
Astbury, W. T., and Bell, F. O., Cold Spring Harbor Symp., 6, 109 (1938).
Carter, R. O., J. Amer. Chem. Soc., 63, 1960 (1941).
Stern, K. G., Yale J. Biol. and Med., 19, 937 (1947); Scientia, 41 (6th Ser.), 74 (1947).
Rights and permissions
About this article
Cite this article
CALVET, F., SIEGEL, B. & STERN, K. Electron Optical Observations on Chromosome Structure in Resting Cells. Nature 162, 305–306 (1948). https://doi.org/10.1038/162305a0
This article is cited by
Zeitschrift f�r Zellforschung und Mikroskopische Anatomie (1957)
Elektronenmikroskopische Studien an Forellenspermatozoen und ihren Zellkernen
The micro-structure of chromatin threads in the metabolic stage of the nucleus
The microstructure and origin of the threadlike bodies isolated from the metabolic nucleus
The isolated chromosomes from erythrocytes of various species of vertebrates
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.