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Isolation from Argemone Oil of Dihydrosanguinarine and Sanguinarine : Toxicity of Sanguinarine

Nature volume 162, pages 265266 (14 August 1948) | Download Citation

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Abstract

ARGEMONE oil has received considerable attention during recent years on account of its alleged etiological role in epidemic dropsy1-4. I pointed out5 certain anomalies of the mustard oil - argemone oil theory of epidemic dropsy and stressed the fact that a definite solution of the problem could only be arrived at by isolating the active principle from argemone oil and the suspected mustard oil, and then showing that these are chemically identical and possess similar toxic properties. Lai et al.2 could not produce any satisfactory evidence on this aspect of the problem.

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Affiliations

  1. Department of Biochemistry, Oxford

    • S. N. SARKAR

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DOI

https://doi.org/10.1038/162265a0

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