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Indicator Yellow and Retinene

Nature volume 162, page 222 (07 August 1948) | Download Citation



IN their interesting article on the "Chemistry of Visual Processes", Ball, Collins, Morton and Stubbs1 consider that Lythgoe‘s indicator yellow2 is a "fortuitous artefact having no direct relevance to visual chemistry". They base this conclusion on the fact that retinene1 may be extracted from bleached retinæ or from bleached visual purple (rhodopsin) solutions by a mixture of acetone, ethanol and light petroleum ether and that "free or loosely bound retinene1 (the final product of bleaching rhodopsin) may combine with any suitable protein or amino-acid which may be available". They regard this fortuitous combination as the means of production of indicator yellow in solution.

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    , , , and , Nature, 161, 424 (1948).

  2. 2.

    , J. Physiol., 89, 331 (1937).

  3. 3.

    , "Annual Review of Biochemistry" 11, 465 (1942).

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    , , and , J. Physiol., 98, 397 (1940).

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    , , and , Proc. Roy. Soc., A, 156, 158 (1936); A, 164, 216 (1938).

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  1. Vision Research Unit, Institute of Ophthalmology, Judd Street, W.C..

    • H. J. A. DARTNALL


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