Letter | Published:

Interaction between Curare and the Potassium Ion at the Motor End Plate

Naturevolume 162page217 (1948) | Download Citation



IN a previous paper1 evidence was presented that there is a relation between the curariform activity of an onium ion and the charge density on its quaternary central atom. A consideration of this theory and of the fact that the paralysing action of curare can be reversed by a fall of temperature2 led to an investigation of the antagonism between curare and the potassium ion3.

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  1. Department of Pharmacology, King‘s College, University of London, Strand, London, W.C.2

    • P. E. B. HOLMES
    • , D. J. JENDEN
    •  & D. B. TAYLOR


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