A Natural Precursor of the Folic Acid Complex

Article metrics


RECENTLY Elvehjem and his co-workers1 have demonstrated the presence, in rat liver homogenates, of a natural precursor capable of conversion by enzymes also present in liver to material having folic acid activity. They base the use of the term ‘folic acid' on the fact that there is no evidence that the material produced is identical with pteroylglutamic acid. The same considerations apply to its use in the present communication.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Olson, O. E., Fager, E. E. C., Buris, R. H., and Elvehjem, C. A., J. Biol. Chem., 174, 319 (1948).

  2. 2

    Hall, D. A., Biochem. J., 41, 299 (1947).

  3. 3

    Hall, D. A., Biochem. J., 42, ix (1948).

  4. 4

    Edlbacher, S., and von Bidder, H., Z. physiol. Chem., 273, 163 (1943).

  5. 5

    Walker, A. C., and Schmidt, C. L. A., Arch. Biochem., 5, 450 (1944).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

HALL, D. A Natural Precursor of the Folic Acid Complex. Nature 162, 178–179 (1948) doi:10.1038/162178b0

Download citation


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.