Interrelations of the Serum Protein in the Thymol Turbidity Test

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THE mechanism of the thymol flocculation test developed by MacLagan in 19441 has in the past four years been the subject of study by several investigators2–5. In the course of a detailed study of the circulating proteins of a patient suffering from advanced liver disease, whose plasma was known to give a strongly positive thymol reaction (18 units), opportunity was taken to examine the observation that normal human albumin would inhibit the thymol reaction3.

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  1. 1

    MacLagan, N. F., Brit. J. Exp. Path., 25, 234 (1944).

  2. 2

    Hangar, F. M., Conference on Liver Injury, New York (1946).

  3. 3

    MacLagan, N. F., and Bunn, D., Biochem. J., 41, 580 (1947).

  4. 4

    Kunkel, H., and Hoagland, C. L., J. Clin. Invest., 26, 1060 (1947).

  5. 5

    MacLagan, N. F., Proc. Biochem. Soc. (in the press).

  6. 6

    Martin, N. H., Brit. J. Exp. Path., 27, 363 (1946).

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MARTIN, N. Interrelations of the Serum Protein in the Thymol Turbidity Test. Nature 162, 145–146 (1948) doi:10.1038/162145a0

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