Interrelations of the Serum Protein in the Thymol Turbidity Test

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Abstract

THE mechanism of the thymol flocculation test developed by MacLagan in 19441 has in the past four years been the subject of study by several investigators2–5. In the course of a detailed study of the circulating proteins of a patient suffering from advanced liver disease, whose plasma was known to give a strongly positive thymol reaction (18 units), opportunity was taken to examine the observation that normal human albumin would inhibit the thymol reaction3.

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References

  1. 1

    MacLagan, N. F., Brit. J. Exp. Path., 25, 234 (1944).

  2. 2

    Hangar, F. M., Conference on Liver Injury, New York (1946).

  3. 3

    MacLagan, N. F., and Bunn, D., Biochem. J., 41, 580 (1947).

  4. 4

    Kunkel, H., and Hoagland, C. L., J. Clin. Invest., 26, 1060 (1947).

  5. 5

    MacLagan, N. F., Proc. Biochem. Soc. (in the press).

  6. 6

    Martin, N. H., Brit. J. Exp. Path., 27, 363 (1946).

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MARTIN, N. Interrelations of the Serum Protein in the Thymol Turbidity Test. Nature 162, 145–146 (1948) doi:10.1038/162145a0

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