Structure of Citrinin

Article metrics


IN view of the recent communication on this topic by Cram1 to the editor of the Journal of the American Chemical Society, we wish to record that in the course of an extensive investigation on the chemistry of citrinin initiated in these laboratories in 1945, the synthesis of 4-methyl-5-ethylresorcinol2, m.p. of anhydrous material 94–95°, was effected in 1946, and the orientations of the two isomeric phenols ‘A' and ‘B' C11H16O3 afterwards established. From these results, inter alia, together with a study of the degradation products of methylated citrinin and of dihydrocitrinin and its ether, evidence has accumulated which leads to the conclusion that citrinin in all probability is best represented by the expression (II).

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Cram, J. Amer. Chem. Soc., 70, 440 (1948).

  2. 2

    Compare Brown, M.Sc. Thesis, May 1947, University of Liverpool.

  3. 3

    Robinson et al., Phil. Trans. Roy. Soc., B, 220, 297 (1931).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

BROWN, J., CARTWRIGHT, N., ROBERTSON, A. et al. Structure of Citrinin. Nature 162, 72–73 (1948) doi:10.1038/162072b0

Download citation

Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.