Letter | Published:

Lipoid Content of the Oxyntic Granules of the Rat‘s Stomach

Nature volume 162, pages 6465 (10 July 1948) | Download Citation



THERE have been a few suggestions in the literature that the granules of the oxyntic cells of the stomach might consist in part of a lipoid material. The evidence for this view has, up to date, been circumstantial, having been based on (a) the tendency of these granules to show some blackening after fixation in fluids containing osmium tetroxide1, and (b) the assumption that, since they can be readily demonstrated by the Altmann – Regaud technique2 and can be supravitally coloured by Janus Green B3 they are mitochondria, and therefore contain lipoid.

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    , , and , Chinese J. Physiol., 1, 305 (1928).

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    , and , Amer. J. Digest. Dis. and Nutr., 3 756 (1936).

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    , and , Anat. Rec., 53, 31 (1932).

  4. 4.

    , personal communication, 1947.

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    , Quart. J. Micro. Sci., 85, 1 (1944).

  6. 6.

    , Quart. J. Micro. Sci., 87, 441 (1946).

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  1. St. Mary‘s Hospital Medical School, Anatomy Department, (University of London), Paddington, London, W.2. March 22.



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