Letter | Published:

Trichothecin : an Antifungal Metabolic Product of Trichothecium roseum Link

Nature volume 162, page 30 (03 July 1948) | Download Citation

Subjects

Abstract

ANTAGONISTIC activity to other fungi by Trichothecium roseum Link (syn. Cephalothecium roseum Corda) has been reported by Whetzel1, Boning2, Koch3 and Greaney and Machacek4. Culture filtrates of T. roseum have been shown to inhibit germination of Botrytis allii conidia5. We have isolated the substance responsible for this activity in crystalline form in yields of 20–30 mgm. per litre of culture filtrate. The name ‘trichothecin' is suggested for the active substance.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    , Ont. Nat. Sci. Bull., 5, 3 (1909).

  2. 2.

    , Phytopath. Z., 6, 113 (1933).

  3. 3.

    , Sci. Agric., 15, 80 (1934).

  4. 4.

    , and , Sci. Agric., 15, 377 (1935).

  5. 5.

    , and , J. Gen. Microbiol., 1, 158 (1947).

Download references

Author information

Affiliations

  1. Imperial Chemical Industries, Ltd., Explosives Division, Research Department, Stevenston, Ayrshire. March 15.

    • G. G. FREEMAN
    •  & R. I. MORRISON

Authors

  1. Search for G. G. FREEMAN in:

  2. Search for R. I. MORRISON in:

About this article

Publication history

Published

DOI

https://doi.org/10.1038/162030a0

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.