Table 4 Influence of long-term pre- and/or probiotic administration on faecal β-glucuronidase and β-glucosidase enzyme activity (mg product formed/g faeces/h), total O and FDW in groups 4 and 5

From: Effect of dietary intervention with different pre- and probiotics on intestinal bacterial enzyme activities

  Enzyme Baseline     Treatment a
    Period 1 Washout 1 Period 2 Washout 2 Period 3 Washout 3 Period 4
Group 4 β-Glucuronidase 0.80±0.31 0.63±0.30 0.75±0.25 0.51±0.30b 0.75±0.32 0.75±0.38   
  β-Glucosidase 0.76±0.26 1.14±0.59c 0.73±0.21 0.61±0.32 0.71±0.39 0.93±0.59   
  FDW (%) 26.19±1.68 25.00±4.73 24.07±4.96 24.76±3.30 25.60±3.90 24.62±4.14   
  FO (g/72 h) 275±99 222±92 317±127 313±151 294±145 240±112   
Group 5 β-Glucuronidase 1.03±0.28 0.82±0.25 0.90±0.15 0.45±0.26d 0.77±0.22 0.88±0.31 0.84±0.15 0.77±0.49
  β-Glucosidase 0.86±0.55 0.93±0.77 0.76±0.44 0.68±0.38 0.74±0.46 0.87±0.56 0.73±0.41 0.82±0.45
  FDW (%) 29.07±7.43 27.90±5.13 26.88±6.60 25.98±5.55 26.11±5.15 25.84±8.43 26.51±4.31 26.03±5.46
  FO (g/72 h) 213±114 205±60 195±56 197±90 237±174 222±115 201±124 251±186
  1. Abbreviations: FDW, faecal dry weight; FO, faecal output; s.d., standard deviation.
  2. Mean±s.d., Wilcoxon test, α=0.05.
  3. aGroup 4: period 1: probiotic B. breve; period 2: prebiotic OF-IN; period 3: placebo. Group 5: period 1: probiotic L. casei Shirota; period 2: prebiotic OF-IN; period 3: placebo; period 4: synbiotic OF-IN+L. casei Shirota.
  4. bSignificantly different from washout 1; P=0.018.
  5. cSignificantly different from baseline; P=0.015.
  6. dSignificantly different from washout 1; P=0.011.