Table 3 Ultrasound density of crow's foot area and grading values of digital photographic images of face in post-menopausal women before and after supplementation with dietary supplement or placebo for 2, 3 and 6 months

From: Effect of a novel dietary supplement on skin aging in post-menopausal women

  Active group (n=38) Placebo group (n=42)
  Baseline Month 2 Month 3 Month 6 Baseline Month 2 Month 3 Month 6 ANOVA P-value a
Face
 Forehead wrinkles 4.2±0.2b 4.1±0.3 3.9±0.2c 3.9±0.2 4.2±0.2 4.2±0.2 4.1±0.2 4.2±0.2 <0.01d
 Periocular wrinkles 5.0±0.2 4.8±0.2 4.5±0.2 4.4±0.2 5.0±0.2 4.9±0.2 4.8±0.2 4.8±0.2 <0.01d
 Perioral fine wrinkles 5.0±0.3 4.9±0.3 4.8±0.3 4.9±0.3 4.9±0.2 4.9±0.2 4.7±0.2 4.8±0.2 NS
 Mottled hyper pigmentation 4.5±0.2 4.3±0.2 4.1±0.2c 3.9±0.2 4.7±0.2 4.6±0.2 4.4±0.2 4.5±0.2 <0.01d
 Teleangiectasia 1.0±0.3 0.9±0.2 0.9±0.2 0.7±0.2 1.6±0.3 1.4±0.3 1.5±0.3 1.5±0.3 NS
 Under eye dark circles 2.4±0.3 2.3±0.3 2.2±0.3c 2.2±0.3 2.8±0.3 2.7±0.3 2.8±0.3 2.7±0.3 NS
 Overall appearance 5.5±0.1 5.2±0.1 4.9±0.1c 4.9±0.2 5.7±0.2 5.5±0.1 5.4±0.2 5.4±0.2 <0.01d
Crow's foot area
 Ultra sound density 41.7±1.1 44.5±1.0 45.8±1.0 49.9±1.0 40.7±0.8 44.2±0.8 46.7±0.9 44.1±0.8 <0.01d
  1. aSignificant difference between active group and placebo at month 6.
  2. bMean values±s.e.m.
  3. cSignificant difference between active group and placebo (P<0.05).
  4. dSignificant difference between active group and placebo at month 6.