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Early short-term infant food supplementation, maternal weight loss and duration of breast-feeding: a randomised controlled trial in rural Senegal

European Journal of Clinical Nutrition volume 60, pages 265–271 (2006)Cite this article

Abstract

Objective:

Early supplementation of breastfed infants may have consequences both for the mother and the child. We hypothesised that it would result in decreased maternal weight loss and in shorter durations of breastfeeding and birth intervals.

Design:

Controlled randomised population-based trial.

Setting:

Six villages in the Sine area of Senegal, West Africa.

Subjects:

Healthy breastfed infants and their mothers, 68 controls and 66 supplemented infants at randomization.

Intervention:

Supplementation with high-energy, nutrient dense food from 4 to 7 months of age, twice daily under supervision of field workers. Both controls and supplemented infants were free to eat other complementary foods. Maternal weight was measured monthly. Dates of breastfeeding cessation and of subsequent births were collected prospectively through weekly demographic surveillance, and were analysed using Cox's regression models and ‘intent-to-supplement’ approach.

Results:

Mean maternal weight gain from 4 to 7 months postpartum tended to be greater in the supplemented group (+0.25 kg/months, 95% confidence interval (CI): −0.07, +0.57). Supplemented infants were breastfed for significantly longer durations than controls (medians: 24.9 and 23.7 months, respectively, P: 0.034). Their adjusted hazard ratio (HR) for breastfeeding cessation was 0.59 (95% CI: 0.40, 0.89). Their mothers had a lower risk of a new birth than mothers of controls (adjusted HR: 0.57, 95% CI: 0.36, 0.92).

Conclusions:

Early short-term infant supplementation tended to decrease maternal postpartum weight loss, but it increased, rather than shortened, the duration of breastfeeding and birth interval.

Sponsorship:

This study was supported by a grant from the French Ministry of Research (Grant 92L0623).

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Acknowledgements

Bernard Maire coordinated the four-country infant supplementation trial, and Jacques Berger, André Cornu (deceased), Francis Delpeuch, Agnès Gartner and Bernard Maire contributed to the study protocol. The authors are grateful to Pape Niokhor Diouf for his dedicated field work and to Adama Marra for management of the Niakhar study area database.

Author information

Authors and Affiliations

  1. Organisme de Recherche sur l'Alimentation et la Nutrition Africaines (ORANA), Dakar, Senegal, France

    C T Ly

  2. Population and Health Service Unit (US 9), IRD (Institut de Recherche pour le Développement), Dakar, Senegal, France

    A Diallo

  3. Epidemiology and Prevention Research Unit (UR 24), IRD, Montpellier, France

    F Simondon & K B Simondon

Authors
  1. C T Ly
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  2. A Diallo
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  3. F Simondon
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  4. K B Simondon
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Corresponding author

Correspondence to K B Simondon.

Additional information

Guarantor: KB Simondon.

Contributors: KBS had the overall responsibility for the trial in Senegal. KBS and FS contributed to the study protocol and CL, AD and KBS supervised field activities. CL and KBS conducted the analysis. All authors contributed to the interpretation of the data and to the manuscript.

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Ly, C., Diallo, A., Simondon, F. et al. Early short-term infant food supplementation, maternal weight loss and duration of breast-feeding: a randomised controlled trial in rural Senegal. Eur J Clin Nutr 60, 265–271 (2006). https://doi.org/10.1038/sj.ejcn.1602311

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