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Drinking deep-sea water restores mineral imbalance in atopic eczema/dermatitis syndrome



The effect of drinking deep-sea water on hair minerals was studied in patients with atopic eczema/dermatitis syndrome (AEDS). Study of hair minerals revealed an imbalance of essential minerals and an increase in toxic minerals in AEDS patients.


After drinking deep-sea water (Amami no Mizu) for 6 months in AEDS patients, hair minerals (essential minerals and toxic minerals), clinical evaluation of the skin symptoms were compared before drinking with after drinking.


After obtaining informed consent, 33 patients (mean age 26 y, range 1–50 y, 13 male and 20 female subjects) with mild to moderate AEDS were enrolled.


After drinking deep-sea water, the levels of the essential mineral, potassium (K), were significantly decreased, while the levels of selenium (Se) increased. On the other hand, drinking deep-sea water significantly decreased the levels of the toxic minerals, mercury and lead. Moreover, after drinking deep-sea water, the skin symptoms were improved in 27 out of 33 patients.


These results indicate that the mineral abnormalities/imbalance may be involved in the pathogenesis of AEDS, and that drinking deep-sea water may be useful in the treatment of AEDS.

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We are indebted to Mr Toyoharu Tsutsui (LVB Preventive Medicine Laboratory) for his kind analysis of the hair minerals and helpful discussions. We wish to express our gratitude to Dr Jun Yoshizawa (Yoshizawa Clinic of Dermatology), Dr Misa Sasai (Kansai Medical University), Dr Yoko Taniguchi (Taniguchi Clinic), Dr Sachie Sumida (Sachie-hihuka Clinic), and Dr Atsuko Ymakami (Matsusaka Chuo General Hospital).

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Correspondence to Y Hataguchi.

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Hataguchi, Y., Tai, H., Nakajima, H. et al. Drinking deep-sea water restores mineral imbalance in atopic eczema/dermatitis syndrome. Eur J Clin Nutr 59, 1093–1096 (2005).

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  • atopic eczema/dermatitis syndrome
  • deep-sea water
  • hair minerals

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