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Consumption of black currants, lingonberries and bilberries increases serum quercetin concentrations

Abstract

Objective: To study serum quercetin concentrations of subjects consuming berries or habitual Finnish diets.

Design: Randomized parallel dietary intervention.

Subjects: Forty healthy men (age 60 y).

Intervention: Twenty subjects consumed 100 g/day of berries (black currants, lingonberries and bilberries) for 8 weeks. Twenty subjects consuming their habitual diets served as controls. Fasting blood samples were obtained 2 weeks prior to the study, at baseline, and at 2, 4 and 8 weeks. Intake of quercetin was assessed from 3 day food records collected at baseline and at 8 weeks.

Results: The serum quercetin concentrations were significantly higher in the subjects consuming berries compared to the control group (P=0.039 ANCOVA with repeated measures). During the berry consumption period the mean serum concentrations of quercetin ranged between 21.4 and 25.3 µg/l in the berry group, which was 32–51% higher compared with the control group. According to 3 day food records, there was no difference in quercetin intake at baseline, but at 8 weeks the intake was 12.3±1.4 mg/day (mean±s.e.m.) in the berry group and 5.8±0.6 mg/day in the control group (P=0.001).

Conclusion: The results indicate that the berries used in this study are a good source of bioavailable quercetin.

Sponsorship: The study was supported by the Academy of Finland, Juho Vainio Foundation and the Finnish Foundation for Cardiovascular Research.

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Acknowledgements

We would like to thank Dr M-L Ovaskainen for providing data on quercetin concentrations of foods and for calculating berry consumption in the 1992 Dietary Survey of Finnish Adults.

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Correspondence to I Erlund.

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Erlund, I., Marniemi, J., Hakala, P. et al. Consumption of black currants, lingonberries and bilberries increases serum quercetin concentrations. Eur J Clin Nutr 57, 37–42 (2003). https://doi.org/10.1038/sj.ejcn.1601513

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Keywords

  • human
  • dietary intervention
  • berries
  • quercetin
  • flavonoids

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