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Magnesium bioavailability from mineral water. A study in adult men

European Journal of Clinical Nutrition volume 56, pages 442–447 (2002)Cite this article

Abstract

Objective: To assess magnesium enteral absorption from a magnesium-rich mineral water.

Design: Experimental study.

Setting: Department of Nuclear Medicine, Brugmann Hospital, Brussels, Belgium.

Subjects: Ten healthy male volunteers in the age range 25–42 y.

Intervention: Each subject completed two sessions in a random order. At one session, they received an oral load of 300 ml of water (containing 1.2 mmol Mg), traced with 28Mg, and at the other session they received an intravenous injection of 28Mg, in order to take into account the metabolism of endogenous magnesium. The dietary consumption was further noted on a weekly diary.

Results: The mean bioavailability was 59.1% (s.d.±13.6). Magnesium absorption and age were significantly inversely correlated (r=−0.68, P=0.035).

Conclusion: Magnesium-rich mineral water is a reliable source of magnesium. Our observation of decreased magnesium absorption with age deserves further investigations.

Sponsorship: The study was sponsored by SEV, Bourg la Reine, France.

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Acknowledgements

We are grateful to Drs D Willems and P Bergmann for the clinical biochemistry and to C Steenwinckel for analysing the diets of the subjects.

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Author notes

  1. M Verhas: Guarantor: M Verhas.

  2. M Verhas, V de La Guéronnière, J-M Grognet, J Paternot, A Hermanne, P Van den Winkel, R Gheldof, P Martin, M Fantino and Y Rayssiguier: Contributors: MV was responsible for conception and realisation of the protocol and redaction. VLG was responsible for initiation of the study, discussion and redaction. JMG was responsible for conception of protocol. JP, RG and PM were responsible for protocol realisation. AH and PVW were responsible for isotope production. MF was responsible for dietary consumption collection and analysis. YR was responsible for results analysis and discussion.

Authors and Affiliations

  1. CHU Brugmann–Free University of Brussels, Brussels, Belgium

    M Verhas, J Paternot, R Gheldof & P Martin

  2. SEV, 92340 Bourg la Reine, France

    V de La Guéronnière

  3. Département des Sciences du Vivant, CEA, Gif sur Yvette, France

    J-M Grognet

  4. Cyclotron Eenheid–Vrije Universiteit Brussels, Brussels, Belgium

    A Hermanne & P Van den Winkel

  5. Laboratoire de Physiologie CHU Dijon, Dijon, France

    M Fantino

  6. Laboratoire de Physiologie, INRA, Clermont-Ferrand-Theix, France

    Y Rayssiguier

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  1. M Verhas
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Correspondence to M Verhas.

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Verhas, M., de La Guéronnière, V., Grognet, JM. et al. Magnesium bioavailability from mineral water. A study in adult men. Eur J Clin Nutr 56, 442–447 (2002). https://doi.org/10.1038/sj.ejcn.1601333

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  • DOI: https://doi.org/10.1038/sj.ejcn.1601333

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