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Effect of tamarind ingestion on fluoride excretion in humans

European Journal of Clinical Nutrition volume 56, pages 82–85 (2002)Cite this article

Abstract

Objective: To evaluate the effect of tamarind (Tamarindus indicus) ingestion on excretion of fluoride in school children.

Design: Randomized, diet-control study.

Subject: Twenty healthy boys were included and 18 of them completed the study.

Interventions: Each subject consumed 10 g tamarind daily with lunch for 18 days at the social welfare boys' hostel. The nutrient composition of the daily diet was constant throughout the experimental period.

Results: Tamarind intake led to significant increase (P<0.001) in the excretion of fluoride in 24 h urine (4.8±0.22 mg/day) as compared to excretion on control diet (3.5±0.22 mg/day). However, excretion of magnesium and zinc decreased significantly (7.11±1.48 mg of Mg and 252.88±12.84 µg of Zn per day on tamarind diet as compared to 23.39±3.68 mg of Mg and 331.78±35.31 µg Zn per day on control diet). Excretion of calcium and phosphorous were not significantly different while creatinine excretion decreased with tamarind intake (225.66±81 mg creatinine/day with tamarind and 294.5±78.76 mg creatinine/day without tamarind).

Conclusion: Tamarind intake is likely to help in delaying progression of fluorosis by enhancing urinary excretion of fluoride.

Sponsorship: National Institute of Nutrition, Hyderabad, India (ICMR).

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Author notes

  1. AL Khandare: Guarantor: AL Khandare.

  2. AL Khandare, GS Rao and N Lakshmaiah: Contributors: ALK formulated the hypothesis, designed and executed the study, and prepared the draft of the paper. GSR did the laboratory assays, and supervised the feeding. NL reviewed the paper and data analysis.

Authors and Affiliations

  1. National Institute of Nutrition, Indian Council of Medical Research, Hyderabad, India

    AL Khandare, GS Rao & N Lakshmaiah

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  1. AL Khandare
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  2. GS Rao
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  3. N Lakshmaiah
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Correspondence to AL Khandare.

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Khandare, A., Rao, G. & Lakshmaiah, N. Effect of tamarind ingestion on fluoride excretion in humans. Eur J Clin Nutr 56, 82–85 (2002). https://doi.org/10.1038/sj.ejcn.1601287

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