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Reaction Between Catalase and Hydrogen Peroxide

Naturevolume 160pages4143 (1947) | Download Citation



WHEN catalase is added to hydrogen peroxide, there is an initial rapid evolution of oxygen which lasts for about two minutes, depending on the peroxide concentration. After this, oxygen is given off at a steady rate which slowly decreases in the course of an hour. This decrease in the rate is undoubtedly due to enzyme destruction, and several kinetic equations have been developed to account for it1. The rapid evolution and the steady rate, however, are inherent features of the peroxide decomposition.

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  1. Yamasaki, E., Tohôhoku Imperial Univ., Sci. Rep., 8, No. 13 (1920). Morgulis, S., J. Biol. Chem., 47, 341 (1921). Northrop, J. H., J. Gen. Physiol., 7, 373(1924–25). Williams, J., J. Gen. Physiol., 11, 309 (1927–28).

  2. Adair, G., Proc. Roy. Soc., A, 108, 627 (1925). Adair, G., Proc. Roy. Soc., A, 109, 292 (1925). Ferry, R. M., and Green, A. A., J. Biol. Chem., 81, 175 (1929).

  3. Keilin, D., and Hartree, E. F., Proc. Roy. Soc., B, 121, 173 (1936).

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  1. Molteno Institute, University of Cambridge

    • DR. P. GEORGE


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