Abstract
MEPACRINE (2-chloro-5-(δ-diethylamino-α-methylbutyl)amino-7-methoxyacridine) has been resolved by Tschelincev and Osetrova1, by the use of what they describe as ααâ2-bromcamphorsulphonic acid.
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References
Tschelincev and Osetrova, J. Gen. Chem. (Russ.), 10, 1978 (1940).
Bacher, Buhs, Hetrick, Reiss and Trenner, J. Amer. Chem. Soc., April 1947.
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BROWN, B., HAMMICK, D. Resolution of Mepacrine. Nature 159, 612 (1947). https://doi.org/10.1038/159612a0
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DOI: https://doi.org/10.1038/159612a0
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