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Acceleration of Thrombin Formation by a Plasma Component

Nature volume 158, pages 708–709 (1946)Cite this article

Abstract

ACCORDING to Quick1, prothrombin is composed of two components A and B, in combination with calcium. Nolf2 carried out experiments from which he formed a similar conclusion. On the other hand, Seegers, Loomis and Vandenbelt3 used purified preparations and concluded that prothrombin consists of a single substance which can act as thrombin precursor.

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References

  1. Quick, A. J., Amer. J. Physiol., 140, 212 (1943).

    Article  CAS  Google Scholar 

  2. Nolf, P., Arch. Internat. de Pharmacodyn. et de Therap., 70, 5 (1945).

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  3. Seegers, W. H., Loomis, E. C., and Vandenbelt, J. M., Arch. Biochem., 6, 69 (1945).

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  4. Fantl, P., and Nance, M., in the press.

  5. Warner, E. D., Brinkhous, K. M., and Smith, H. P., Amer. J. Physiol., 114, 667 (1936).

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Authors and Affiliations

  1. Baker Medical Research Institute, Alfred Hospital, Melbourne

    P. FANTL & M. NANCE

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  1. P. FANTL
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  2. M. NANCE
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FANTL, P., NANCE, M. Acceleration of Thrombin Formation by a Plasma Component. Nature 158, 708–709 (1946). https://doi.org/10.1038/158708a0

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