Letter | Published:

Catatorulin Effect of Aneurin Disulphide

Nature volume 158, page 707 (16 November 1946) | Download Citation

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Abstract

ANEURIN disulphide1, formed by opening of the thiazole ring and oxidation to the—S—S—form, does not give the thiochrome reaction, unless suitably reduced by cysteine; it was reported to have some 60 per cent of the biological activity of aneurin, when given orally to animals. I have found in catatorulin tests, by methods previously described2, with the deficient pigeon brain that it is at least as active as aneurin (Table 1).

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References

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    Ber., 73, 941 (1940). (See also, , and , Z. Physiol., C, 267, 210 (1941).)

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Affiliations

  1. Department of Biochemistry, Oxford. Oct. 19.

    • R. A. PETERS

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DOI

https://doi.org/10.1038/158707a0

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