Abstract
NOLAN and his co-workers have described1,2,3 the isolation from the lichen Buellia canescens, of diploicin, and from constitutional studies have provisionally assigned to it structure I. Diploicin is insoluble in water, and for this reason its antibacterial activity was not examined by us in vitro. Iodinated and chlorinated phenyl ethers of type II have been shown, however, by Burger, Brindley, Wilson and Bernheim4 to have tuberculostatic activity in vitro. A closer study of the diploicin molecule was, therefore, considered desirable.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Nolan, Sci. Proc. Roy. Dub. Soc., 21, 67 (1935).
Spillane, Keane and Nolan, Sci. Proc. Roy. Dub. Soc., 21, 333 (1936).
Davidson, Keane and Nolan, Sci. Proc. Roy. Dub. Soc., 23, 151 (1943).
Burger, Brindley, Wilson and Bernheim, J. Amer. Chem. Soc., 67 1416 (1945).
Rich, “The Pathogenesis of Tuberculosis” (Thomas, Springfield, Illinois, 1944).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
BARRY, V. The Thyroid and Tuberculosis. Nature 158, 131–132 (1946). https://doi.org/10.1038/158131d0
Issue Date:
DOI: https://doi.org/10.1038/158131d0
This article is cited by
-
Antibacterial substances from lichens
Economic Botany (1952)
-
Pharmakologie der Schilddr�sent�tigkeit
Naunyn-Schmiedebergs Archiv f�r Experimentelle Pathologie und Pharmakologie (1951)
-
Antitubercular Activity of Diphenyl Ethers and Related Compounds
Nature (1947)
-
Die antibakterielle Wirkung der Usninsäure auf Mykobakterien und andere Mikroorganismen
Experientia (1947)
-
The Thyroid and Tuberculosis
Nature (1946)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.