Thermostable Endotoxin of Rickettsiae


Kligler and Oleinik1 reported the presence of a labile toxin in yolksac cultures of Rickettsise. The following experiments were designed in order to test whether the toxic effects of Rickettsiæ are wholly brought about by this labile toxin, or are due also to the action of a thermostable toxin.

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  1. 1

    Kligler, I. J., and Oleinik, E., Nature, 154, 462 (1940).

  2. 2

    Zahl, P. A., and Hutner, S. H., Proc. Soc. Exp. Biol. and Med., 56, 156 (1944).

  3. 3

    Cameron, G. R., Delafield, M. E., and Wilson, J., J. Path, and Bact., 51, 223 (1940).

  4. 4

    Olitzki, L., Avinery, Sh., and Bendersky, J., J. Immunol., 41, 361 (1941).

  5. 5

    Schwartzman, G., "Phenomena of Local Tissue Reactivity" (Paul B. Hoeber, Inc., New York, 1937).

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OLITZKI, L., OLEINIK, E., CZACZKES, J. et al. Thermostable Endotoxin of Rickettsiae. Nature 157, 552 (1946) doi:10.1038/157552a0

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