Effect of Acute Starvation on the Adrenals of the White Rat


SINCE McCarrison1 in 1919 and Vincent2 in 1920 recorded the enlargement of the adrenals in the pigeon and the rat as a result of acute starvation, this anomalous result has been generally considered a hypertrophy3,4 ; no other tissue enlarges from such treatment.

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  1. 1

    McCarrison, R., Indian J. Med. Res., 6, 275 (1919).

  2. 2

    Vincent, S., and Hollenberg, M. S., Endocrin, 4, 408 (1920); J. Physiol., 54, P. lxix (1920–21).

  3. 3

    Tepperman, J., Engel, F. L., and Long, C. N. H., Endocrin, 32, 373 (1943).

  4. 4

    Goldzieher, M. A., "Adrenal Glands in Health and Disease" (Phila., 1945)

  5. 5

    McCarrison, R., "Studies in Deficiency Diseases" (London, 1921).

  6. 6

    Marrian, G. F., Biochem. J., 22, 836 (1928).

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CAMERON, A., CARMICHAEL, J. Effect of Acute Starvation on the Adrenals of the White Rat. Nature 157, 483 (1946) doi:10.1038/157483a0

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