NEAR the end of the nineteenth century, Ehrlich first directed attention to the similarity between enzyme and immune reactions on the basis of their highly specific character. "Immuno-Catalysis" examines this similarity in the light of modern work, and, further, puts forward a detailed case to support the view that the formation of a specific antibody in response to the introduction of a given antigen fulfils all the criteria of enzyme-catalysed systems, suggesting that antigen (catalyst) merely directs the formation from serum globulin (substrate) of antibody (product), which in the immune reaction acts as a specific enzyme inhibitor.


    By Prof. M. G. Sevag. Pp. xv + 272. (Springfield, Ill., and Baltimore, Md.: Charles C. Thomas; London: Baillière, Tindall and Cox, 1945.) 4.50 dollars.

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    Immuno-Catalysis. Nature 156, 517 (1945).

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