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Lecithin and Venom Hæmolysis

Abstract

IT is well known that different species of erythrocytes exhibit wide variations in their susceptibility to venom hæmolysis. Some, such as those of the sheep, the goat and the ox, are totally resistant, while others, like those of the guinea pig and the dog, are very susceptible. Venoms also vary greatly in their hæmolytic activity. Those obtained from the Colubridæ class are hæmolytic in varying degrees, while the Viperidæ species of snakes yield venoms which are mostly non-hæmolytic. In the presence of a trace of lecithin, however, all species of erythrocytes susceptible or refractory lyse very readily with all venoms irrespective of their nature.

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ROY, A. Lecithin and Venom Hæmolysis. Nature 155, 696–697 (1945). https://doi.org/10.1038/155696a0

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  • DOI: https://doi.org/10.1038/155696a0

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