Abstract
DURING the course of investigations on the production of immunity to foot-and-mouth disease the intracutaneous route of vaccination has been considered. It has generally been recognized that one disadvantage of this route in large animals is that, owing to the pressure required, only a small volume of inoculum can be injected at one site. Various attempts have been made in the past to overcome this difficulty, and by means of compressed air Curasson, Dischamps and Andryesky1 found it practicable to inject 10 c.c. of their rinderpest vaccine into the skin of the bovine scrotum and vulva.
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References
Curasson, G., Dischamps, A., and Andryesky, P., Bull. Acad. vét. Fr., 2, 383 (1929).
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HENDERSON, W. Intracutaneous Injection of Cattle. Nature 152, 629–630 (1943). https://doi.org/10.1038/152629b0
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DOI: https://doi.org/10.1038/152629b0
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