Letter | Published:

Production of Penicillin



PENICILLIN, the metabolic product of Penicillium notatum, discovered by Fleming in 1929, has been shown to be a chemotherapeutic agent of great importance. The exceedingly high bacteriostatic potency of this substance, together with its low toxicity to tissue cells, are such that penicillin has been described as “the most powerful antibacterial agent with predominantly bacteriostatic action so far known”1, and its value in human therapy has already been demonstrated2.

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  1. 1

    Abraham and Chain, Brit. J. Exp. Path., 23, 103 (1942).

  2. 2

    Abraham, Chain, Fletcher, Florey, Gardner, Heatley and Jennings . Lancet, 241, 177 (1941).

  3. 3

    Fleming, A., Brit. J. Exp. Path., 10, 226 (1929).

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