Abstract
THE discovery of the synthetic œstrogens put at our disposal substances which had the great advantage of being highly active when given by mouth. Of these, stilbœstrol has been extensively used and has proved of great value. This substance, however, has only a short period of action so that clinically it has to be given at frequent intervals in order to produce a sustained effect.
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References
Robson, J. M., Quart.,J. Exp. Physiol., 28, 195 (1938).
Robson, J. M., Schönberg, A., and Fahim, H. A., NATURE, 142, 292 (1938).
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ROBSON, J., SCHÖNBERG, A. A New Synthetic Œstrogen with Prolonged Action when Given Orally. Nature 150, 22–23 (1942). https://doi.org/10.1038/150022a0
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DOI: https://doi.org/10.1038/150022a0
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