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Artificial Hibernation

Abstract

AS I have already shown in preliminary communications1,2, artificial hibernation is produced in hedgehogs in autumn by giving them injections of magnesium simultaneously with insulin and transferring the animals to an ice-box. Thereby, for example, the heat regulation of the animals was disturbed, and they passed from a warm-blooded state into a cold-blooded one. At the same time, the blood sugar value was decreased to the level of that found in normal hibernation. In the first series of experiments I employed comparatively large amounts of magnesium and insulin. Similar amounts of insulin given without magnesium always caused fatal hypoglycæmia.

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References

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    Suomen Kemistilehti, B, 11, 29 (1938).

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SUOMALAINEN, P. Artificial Hibernation. Nature 144, 443–444 (1939). https://doi.org/10.1038/144443a0

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