A Benzpyrene Tumour Strain in Hamsters with Tendency to Metastasis Formation


EXPERIMENTS on the hamster with carcinogenic substances have so far been described only in a short communication by Gye and Foulds1. Our experiments were made with the view of demonstrating whether the tumours caused in the hamster by carcinogenic substances show any peculiarities with regard to formation and course. 40 hamsters (Cricetus aureus) were given subcutaneous injections of 0·25 c.c. of a 1 per cent solution of benzpyrene Meurice. 93 per cent of the animals developed tumours after a latent period of three months on the average. Histologically they were polymorph cell sarcomata.

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  1. 1

    Amer. J. Canc., 35, 103 (1939).

  2. 2

    J. Path. Bact., 47, 501 (1938).

  3. 3

    NATURE, 143, 223 (1939).

  4. 4

    Bull. Assoc. franç. Etude Canc., 32, 193 (1939).

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HALBERSTAEDTER, L. A Benzpyrene Tumour Strain in Hamsters with Tendency to Metastasis Formation. Nature 144, 377–378 (1939). https://doi.org/10.1038/144377b0

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